Urease Enzyme

The enzyme is a functional unit of cell metabolism. Working with an orderly sequence, the enzyme catalyzes the reaction gradually describing hundreds of nutrient molecules, reactions which store and convert chemical energy, and that makes the macro molecular pre cursor cells from simple. Among a number of enzymes that participate, there is a special group of enzymes known as the regulator, which can recognize various cues metabolic and catalytic change speed in accordance with the received signal. Through its activities, well-coordinated enzyme systems, resulting in a harmonious relationship among a number of different metabolic activities, which are required to sustain life.

In the early twentieth century, Emil Fischer did the first systematic study on the specificity of the enzyme. Other researchers studying the kinetics of enzyme activity and developing the theory of action of the enzyme. However, barulahpada in 1926, the enzyme can be isolated in crystalline form for the first time. This enzyme is urease, which is obtained from extracts of pea by James Sumner at Cornell University. Sumner found that urease crystal composed entirely of protein. Therefore, he argued that all enzymes are proteins, but the German biochemist Richard Willstater stressed that the enzyme is a low molecular weight compounds and that the protein is a low molecular weight compounds and that the protein found in crystalline urease is a pollutant. It was only in 1930, after John Northrop and his colleagues crystallized pepsin and trypsin, and found both of them are also proteins, enzymes of protein nature secra widely accepted. This was followed by an intensive period will penelititan enzymes that catalyze reactions of cell metabolism. Now, some 2000 types of enzymes have been identified, each berebda catalyze chemical reactions. Hundreds of enzymes have been obtained in pure crystalline form.

Many enzymes that have been named by adding the suffix ase to the name of the substrate. Thus, urease catalyzes the hydrolysis of urea, and arginase catalyzes the hydrolysis of arginine. But many enzymes that have been called by not explaining substrates such as pepsin and trypsin. Also the fact that a similar enzimyang known with two or more names, or that two different enzymes have been given the same name. Therefore, and because other things are still vague, also by continuing meningkatnyaenzim newly discovered by international agreement. This system is put enzymes into six main classes, each with subclasses, based on the type of reaction dikatalisa. Each enzyme is assigned to the four levels of class number and given a systematic name, which identifies the catalyzed reaction.